Which of the following is the main cause of hepatic encephalopathy in patients with cirrhosis
Question : Which of the following is the main cause of hepatic encephalopathy in patients with cirrhosis?
A. Elevated serum ammonia levels
B. Hypoglycemia
C. Hyperbilirubinemia
D. Hypoalbuminemia
Answer: A
Explanation: In patients with cirrhosis, the liver's ability to clear ammonia is reduced, leading to elevated serum ammonia levels. Ammonia crosses the blood-brain barrier and impairs central nervous system function, which is the main pathogenesis of hepatic encephalopathy. Hypoglycemia, hyperbilirubinemia, and hypoalbuminemia are common complications of cirrhosis but not the main causes of hepatic encephalopathy. Hence, the correct answer is A.
