Which of the following is the most common cause of peptic ulcer disease
Question : Which of the following is the most common cause of peptic ulcer disease?
A. Nonsteroidal anti-inflammatory drugs (NSAIDs) use
B. Helicobacter pylori infection
C. Stress
D. Smoking
Answer: B
Explanation: Helicobacter pylori infection is the most common cause of peptic ulcer disease, accounting for about 70%-90% of duodenal ulcers and 60%-70% of gastric ulcers. NSAIDs use is the second most common cause; stress and smoking are risk factors but not the main causes. Hence, the correct answer is B.

